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The World Health Organization estimates that by 2030 COPD be the world’s fourth leading cause of death, after heart disease, stroke and AIDS, and the increase in deaths is predicted to be greater in developing countries than in rich countries. The neglect of COPD by clinicians, researchers, and pharmaceutical companies, Professor Barnes says in his essay in PLoS Medicine , is is considered mainly due to COPD as self-inflicted and also because the cause of the disease is generally irreversible . Irreversible . (more…)